- 029-86354885
- 18392009562
IR-825 CAS1558079-49-4 用于腫瘤光熱光動力治療-僅科研
西安瑞禧生物科技有限公司可以提供一種用于腫瘤癌癥細胞的光熱治療和光動力治療的近紅外熒光染料IR-825,該產品的吸收波長是810nm,發射波長是830nm,該產品的末端帶有羧基COOH活性基團可以參與反應連接其他分子,這個產品的造價要低于ICG-COOH,可以廣泛用于腫瘤的光熱治療。我公司制備的IR-825純度95.4%,可以溶解在二氯甲烷、甲醇、DMF、DMSO里。
特別說明:該產品僅僅用于科學研究,不用于人體及藥物開發
IR-825 from ruixibio is a near-infrared dye (NIR). IR-825, after encapsulated into nanoparticles may be useful for cancer photothermal and photodynamic therapy. IR-825 nanoparticles showed pH-dependent fluorescence emission and excellent near-infrared (NIR) irradiation of cancer cells targeted in vitro to provide cytotoxicity. IR-825 nanoparticles showed efficient tumor homing together with rapid renal excretion behaviors, as revealed by MR imaging and confirmed by biodistribution measurement. Notably, when irradiated with an 808 nm laser, tumors on mice with IR-825 nanoparticle injection are completely eliminated without recurrence within 60 days, demonstrating the high efficacy of photothermal therapy.
Certificate of Analysis
General properties:
Name:IR825
Molecular Weight:823.4 Dalton
Cat.#:R-H-6012
Lot.#: RM017172
Date of Analysis:2018.01.09
Recommended Retest date:2019.01.09
Stability: 12 months
Storage: -20°C in the dark
Structure
Items |
| Specification | Results |
Appearance |
| solid | solid |
1H NMR |
| Identical to the structure | Identical to the structure |
Foreign Material |
| None | None |
Purity by HPLC |
| >95% | 95.4% |
Report Date: 2018.01.09 |
|
|
Attachment 1: HPLC
Attachment 2: MS
序號 | 新聞標題 | 瀏覽次數 | 作者 | 發布時間 |
---|---|---|---|---|
1 | 抗氧化小分子70831-56-0,菊苣酸Cichoric Acid,6537-80-0的制備過程 | 750 | 瑞禧生物 | 2023-03-30 |
2 | 活性氧ROS小分子Dapsone,cas:80-08-0,氨苯砜的制備過程-瑞禧科研 | 667 | 瑞禧生物 | 2023-03-30 |
3 | HBPS-N3,Azide-PEG-HBPS,疊氮化超支化聚苯乙烯高分子聚合物的制備過程 | 779 | 瑞禧生物 | 2023-03-17 |
4 | l-PS-PhN3,Azide疊氮Azido偶聯線性聚苯乙烯雙鏈的制備過程 | 723 | 瑞禧生物 | 2023-03-17 |
5 | N3-PS-N3,Azido-PS-Azido/Azide,雙疊氮官能團修飾聚苯乙烯的制備方法 | 682 | 瑞禧生物 | 2023-03-17 |
6 | PS-N3,Azido-PS,疊氮Azide修飾聚苯乙烯/高分子聚合物的制備過程 | 853 | 瑞禧生物 | 2023-03-17 |
7 | Azido-PEG2-t-Butylester/1271728-79-0,疊氮N3/ZAD修飾叔丁酯化合物的制備方法 | 698 | 瑞禧生物 | 2023-03-14 |