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Home > Products > APIs cancer> Hot APIs cancer> Elafibranor;GFT505;GFT-505;GFT 505,CAS824932-88-9
Elafibranor;GFT505;GFT-505;GFT 505,CAS824932-88-9
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R-SX-531 1 ¥ 1
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分子量 384.49
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CAS號 824932-88-9
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Elafibranor is an agonist of the peroxisome proliferator-activated receptor-α and peroxisome proliferator-activated receptor-δ. Elafibranor improves insulin sensitivity, glucose homeostasis, and lipid metabolism and reduces inflammation.We assessed the safety and efficacy of elafibranor in an international, randomized, double-blind placebo-controlled trial of patients with nonalcoholic steatohepatitis (NASH). Elafibranor (GFT505) is a dual PPARα/δ agonist that has demonstrated efficacy in disease models of nonalcoholic fatty liver disease (NAFLD)/NASH and liver fibrosis. Elafibranor confers liver protection by acting on several pathways involved in NASH pathogenesis, reducing steatosis, inflammation, and fibrosis.西安瑞禧生物提供各種抑制劑材料。
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